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Technology

The CARILLON® Mitral Contour System™ is designed to be positioned in the coronary sinus and great cardiac vein using standard cardiac catheterization techniques. The CARILLON implant is a fixed length, double anchor device designed to plicate the tissue next to the mitral valve annulus during the deployment process.
 

Carillon Implant



Carillon Delivery Handle

The distal anchor is positioned deep in the coronary sinus near the anterior commissure of the mitral valve. To accommodate the variable anatomy of the coronary sinus and great cardiac vein, tension is then placed on the delivery system to plicate the tissue and optimize the degree of functional mitral regurgitation ("FMR") reduction. Finally the proximal anchor is positioned near the coronary sinus ostium to secure the reduction in mitral annular area. Recognizing the proximity of the coronary arteries to the coronary sinus, the CARILLON implant is designed to be recaptured and another CARILLON implant repositioned should alterations of coronary flow be detected during the implant procedure. The benign nature of the anchor design allows for subsequent deployments if a first device has been recaptured.

Below is an animation of the implant procedure:

(iPhone/iPad users click here)

Potential benefits of percutaneous annuloplasty for functional mitral regurgitation, using the CARILLON Mitral Contour System:

• Simple procedure which often takes less than one hour

• Acute efficacy (MR reduction) is controlled / adjusted by the physician peri-operatively

• Echo results are observable during the procedure

• Complementary therapies, such as bi-ventricular pacing, are not precluded by virtue of the anchor shape

• Peri-procedural recapture feature allows for repositioning of the device and thus the ability to optimize the reduction of FMR

• The devices' benign design is compatible with the surrounding anatomy and allows for subsequent deployments if a first device has been recaptured.

Below is an animation of the implant recapture process:

(iPhone/iPad users click here)

CAUTION: Investigational Device. Exclusively for Clinical Investigation.